- 《英文msh詞典》Insertional Mutageneses,Viral
- [入口詞] Insertional Mutageneses,Viral
- [主題詞] Mutagenesis,Insertional
- [英文釋義] Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA can be inserted into or adjacent to a cellular proto-oncogene. Insertion of the provirus can cause mutations by interrupting coding sequences or regulatory elements,or cause unregulated expression of the proto-oncogene resulting in tumor formation.
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